What happens during the Link Reaction you ask???
Well....
Once the pyruvate molecules form glycolysis are in the
mitochondrion, enzymes in the matrix of the mitochondrion remove hydrogen and
carbon dioxide from the pyruvate. This is called oxidation (removal of hydrogen
or addition of oxygen) and decarboxylation (removal of carbon dioxide).
Therefore, the process is called oxidative decarboxylation. The hydrogen
removed is accepted by NAD+. The link reaction results in the formation of an
acetyl group. This acetyl group is then accepted by CoA and forms acetyl CoA!
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